Literature Agent

Search and synthesize scientific literature across multiple sources.

The Literature Agent is a specialized subagent that searches, retrieves, and synthesizes scientific literature from multiple sources.

Literature Agent Workflow

Capabilities

The Literature Agent searches across:

  • PubMed - Biomedical literature
  • ArXiv - Preprints in biology and related fields
  • Clinical Trials - ClinicalTrials.gov registry
  • Patents - Patent databases
  • Biochemical Databases - UniProt, ChEMBL, and more

Intelligent Reranking

Results are processed through a two-stage reranking pipeline:

  1. Embedding-based ranking - Semantic similarity to your query
  2. LLM-based reranking - Contextual relevance scoring

Answer Synthesis

The agent doesn't just return papers—it synthesizes findings into coherent answers with citations, highlighting key findings and contradictions in the literature.

Example Queries

The Literature Agent handles various query types:

"Find papers on PCSK9 inhibitors and cardiovascular outcomes"
"What is known about the mechanism of action of metformin in aging?"
"Search for clinical trials investigating senolytics in humans"
"Find recent reviews on gut microbiome and neurodegeneration"

Integration with BIOS

Within a BIOS research session, the Literature Agent is automatically invoked when the planner identifies literature search tasks. Results are fed back into the research cycle for hypothesis generation.